Active Protocols as Lead Node

CTN-0154: EMS Initiated Buprenorphine for Opioid Use Disorder

Gail D'Onofrio, MD, MS (Co-Lead Investigator)

Andrew Herring , MD (Co-Lead Investigator)

affiliation Pacific Northwest Node

Gerard Carroll, MD, FAAEM, EMT-P (Co-Lead Investigator) affiliation Cooper Medical School of Rowan University

NEC Study Team Members

Marek Chawarski, PhD (Co-I)

CTN-0146: A Cohort Study of Pain, Psychological, and Drug Use Outcomes of Adolescents After Major Surgery

Sharon Levy, MD, MPH (Lead Investigator)

Joseph Cravero, MD (Co-Lead Investigator)

NEC Study Team Members

Elissa Weitzman, ScD, MSc (Co-I)

CTN-0145: High vs Standard Buprenorphine ED Initiation

Kathryn Hawk, MD, MHS (Lead Investigator)

Andrew Herring , MD (Lead Investigator)

affiliation Pacific Northwest Node

Gail D'Onofrio, MD, MS (Lead Investigator)

NEC Study Team Members

Marek Chawarski, PhD (Co-I)

CTN-031: Methadone or Enhanced Buprenorphine to Address Retention Among Patients Not Optimally Benefitting from Office-based Buprenorphine - a Hybrid Effectiveness/Implementation Trial (EMBOSS)

David Fiellin, MD (Lead Investigator)
Paul Joudrey, MD, MPH (Co-Lead Investigator)
affiliation Appalachian Node
NEC Study Team Members
Marek Chawarski, PhD (Co-I)
Ryan McNeil, PhD (Co-I)
Jeanette Tetrault, MD (Co-I)
Zoe Weinstein, MD, MD (Co-I)

CTN-0126: Longitudinal Follow-Up of Individuals with Opioid Use Disorder

Kathryn McHugh, PhD (Lead Investigator)
Kathryn Hefnew, PhD (Lead Investigator)
affiliation Emmes
Rebecca Ottesen (Lead Investigator)
affiliation Emmes
Matisyahu Shulman, MD (Lead Investigator)
affiliation Emmes

CTN-0100: Optimizing Retention, Duration, and Discontinuation Strategies for Opioid Use Disorder Pharmacotherapy (NIH HEAL Initiative)

Lead Node: New York
Roger Weiss, MD (Lead Investigator)
Edward V. Nunes, Jr., MD (Lead Investigator)
affiliation New York Node
John Rotrosen, MD (Lead Investigator)
affiliation New York Node
Node Participation
R. Kathryn McHugh, PhD (Study Team Co-I)
Genie L. Bailey, MD (Site PI)
John Hamilton, LMFT, LADC (Site PI)
Natalie Lender, MD (Site PI)
Scott Provost, MSW, MM
(Senior Project Manager)

Completed Studies

CTN-0079-A1 a sub-study of CTN-0099: Emergency Department INitiated upreNOrphine and VAlidaTIOn Network Trial (ED-INNOVATION) (NIH HEAL Initiative)

Ryan McCormack, MD (Lead Investigator) affiliation New York Node, Kathryn Hawk, MD, MHS (Co-Lead Investigator)

CTN-0080-A2 a sub-study of CTN-0080: Qualitative interviews of pregnant patients of color with OUD

Davida Schiff, MD (Lead Investigator)

CTN-0099: Emergency Department INitiated bupreNOrphine and VAlidaTIOn Network Trial(ED-INNOVATION)(NIH HEAL Initiative)

Gail D’Onofrio, MD, MS (Lead Investigator), David Fiellin, MD (Lead Investigator)

NEC Study Team Members: James Dziura, MD, MHS (Co-I), E. Jennifer Edelman, MD, MHS (Co-I), Kathryn Hawk, MD, MHS (Co-I), Michael Pantalon, PhD (Co-I)

CTN-0099 Supplement: Racial/Ethnic Disparities in Addiction Treatment Access for Opioid Use Disorder from the Emergency Department

Edouard Coupet Jr, MD, MS (Lead Investigator)

CTN-0099-A a sub-study of CTN-0099: Emergency Department INitiated BupreNOrphine and VAlidaTIOn Network Trial (ED-INNOVATION) (NIH HEAL Initiative)

Gail D'Onofrio, MD, MS (Lead Investigator)

CTN-0112: Optimal Policies to Improve Methadone Maintenance Adherence Longterm (OPTIMMAL)

A. Robin Williams, MD, MBE (Lead Investigator) affiliation New York Node

NEC Study Team Members: Lynn Madden, PhD, MPA (Site Investigator)

CTN-0116: Pharmacist-Integrated Model of Medication Treatment for Opioid Use Disorder

Lisa Marsch, PhD (Lead Investigator) affiliation Northeast Node

NEC Study Team Members: David Fiellin, MD (Study Co-Lead Investigator)

CTN-0122: Comprehensive Meta-Analysis of CTN Treatment Outcomes by Race and Sex

Sarah Mennenga, PhD (Lead Investigator) affiliation New York Node

NEC Study Team Members: Angela Haeny, PhD (Co-I), Carolyn Sartor, PhD (Co-I), Shelly Greenfield, MD, MPH Co-I), R. Kathryn McHugh, PhD (Co-I)

CTN-0125: Integrative Data Analysis of CTN Studies to Examine the Impact of Psychosocial Treatments for Black People who use Cocaine

Kathy Burlew, PhD (Co-Lead Investigator) affiliation Ohio Valley Node , Lesia Ruglass, PhD (Co-Lead Investigator) affiliation New York Node
NEC Study Team Members: Angela Haeny PhD, Maria Crouch PhD

Active Protocols as Lead Node

CTN-0154: EMS Initiated Buprenorphine for Opioid Use Disorder

Gail D'Onofrio, MD, MS (Co-Lead Investigator)

Andrew Herring , MD (Co-Lead Investigator)

affiliation Pacific Northwest Node

Gerard Carroll, MD, FAAEM, EMT-P (Co-Lead Investigator) affiliation Cooper Medical School of Rowan University

NEC Study Team Members

Marek Chawarski, PhD (Co-I)​​​

CTN-0146: A Cohort Study of Pain, Psychological, and Drug Use Outcomes of Adolescents After Major Surgery

Sharon Levy, MD, MPH (Lead Investigator)

Joseph Cravero, MD (Co-Lead Investigator)

NEC Study Team Members

Elissa Weitzman, ScD, MSc (Co-I)​

CTN-0145: High vs Standard Buprenorphine ED Initiation

Kathryn Hawk, MD, MHS (Lead Investigator)

Andrew Herring , MD (Lead Investigator)

affiliation Pacific Northwest Node

Gail D'Onofrio, MD, MS (Lead Investigator)

NEC Study Team Members

Marek Chawarski, PhD (Co-I)

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CTN-031: Methadone or Enhanced Buprenorphine to Address Retention Among Patients Not Optimally Benefitting from Office-based Buprenorphine - a Hybrid Effectiveness/Implementation Trial (EMBOSS)

David Fiellin, MD (Lead Investigator) Paul Joudrey, MD, MPH (Co-Lead Investigator) affiliation Appalachian Node NEC Study Team Members Marek Chawarski, PhD (Co-I) Ryan McNeil, PhD (Co-I) ​Jeanette Tetrault, MD (Co-I) Zoe Weinstein, MD, MD (Co-I)

CTN-0126: Longitudinal Follow-Up of Individuals with Opioid Use Disorder

Kathryn McHugh, PhD (Lead Investigator) Kathryn Hefnew, PhD (Lead Investigator) affiliation Emmes Rebecca Ottesen (Lead Investigator) affiliation Emmes Matisyahu Shulman, MD (Lead Investigator) affiliation Emmes

CTN-0100: Optimizing Retention, Duration, and Discontinuation Strategies for Opioid Use Disorder Pharmacotherapy (NIH HEAL Initiative)

Completed Studies

NEC Study Team Members: Lynn Madden, PhD, MPA (Site Investigator)

CTN-0116: Pharmacist-Integrated Model of Medication Treatment for Opioid Use Disorder

Lisa Marsch, PhD (Lead Investigator) affiliation Northeast Node

NEC Study Team Members: David Fiellin, MD (Study Co-Lead Investigator)

​

CTN-0122: Comprehensive Meta-Analysis of CTN Treatment Outcomes by Race and Sex

Sarah Mennenga, PhD (Lead Investigator) affiliation New York Node

NEC Study Team Members: ​Angela Haeny, PhD (Co-I), Carolyn Sartor, PhD (Co-I), Shelly Greenfield, MD, MPH Co-I), R. Kathryn McHugh, PhD (Co-I)

CTN-0125: Integrative Data Analysis of CTN Studies to Examine the Impact of Psychosocial Treatments for Black People who use Cocaine

Kathy Burlew, PhD (Co-Lead Investigator) affiliation Ohio Valley Node , Lesia Ruglass, PhD (Co-Lead Investigator) affiliation New York Node NEC Study Team Members: Angela Haeny PhD, Maria Crouch PhD

Marek Chawarski, PhD (Co-I)

Elissa Weitzman, ScD, MSc (Co-I)

David Fiellin, MD (Lead Investigator)
Paul Joudrey, MD, MPH (Co-Lead Investigator)
affiliation Appalachian Node
NEC Study Team Members
Marek Chawarski, PhD (Co-I)
Ryan McNeil, PhD (Co-I)
Jeanette Tetrault, MD (Co-I)
Zoe Weinstein, MD, MD (Co-I)

Kathryn McHugh, PhD (Lead Investigator)
Kathryn Hefnew, PhD (Lead Investigator)
affiliation Emmes
Rebecca Ottesen (Lead Investigator)
affiliation Emmes
Matisyahu Shulman, MD (Lead Investigator)
affiliation Emmes

NEC Study Team Members: Angela Haeny, PhD (Co-I), Carolyn Sartor, PhD (Co-I), Shelly Greenfield, MD, MPH Co-I), R. Kathryn McHugh, PhD (Co-I)

Kathy Burlew, PhD (Co-Lead Investigator) affiliation Ohio Valley Node , Lesia Ruglass, PhD (Co-Lead Investigator) affiliation New York Node
NEC Study Team Members: Angela Haeny PhD, Maria Crouch PhD